Healthwise® News Release:

Two Medicines Removed from Market

FOR IMMEDIATE RELEASE

 

BOISE, Idaho, April 2, 2007—The makers of two medicines, pergolide (Permax) and tegaserod (Zelnorm), have agreed to stop selling them because they may cause serious side effects, according to the U.S. Food and Drug Administration (FDA).
  • Pergolide (Permax) is mainly used to treat Parkinson’s disease. It will no longer be sold, because it may damage your heart valves. But stopping pergolide too quickly can be dangerous, so if you are taking this medicine, don’t try to stop on your own. It’s important to talk to your doctor first. There are other medicines that work like pergolide and can treat Parkinson’s disease.

  • Tegaserod (Zelnorm) is used to treat chronic constipation and irritable bowel syndrome. If you are taking this medicine, you may have a higher chance of heart attack, stroke, and chest pain. It is okay to stop taking tegaserod on your own. Call your doctor to talk about other medicines you can try. Call 911 right away if you have chest pain, shortness of breath, dizziness, sudden weakness or trouble walking or talking, or other symptoms of a heart attack or stroke.

 

For more information about pergolide, see the FDA public health advisory at www.fda.gov/cder/drug/advisory/pergolide.htm. For more information on tegaserod, see the FDA public health advisory at http://www.fda.gov/cder/drug/advisory/tegaserod.htm.

 

You can find more information on the FDA Web site at http://www.fda.gov/medwatch/index.html.

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